Identify whether the enrolling entity is an institutional provider (filing CMS-855A) or a DMEPOS supplier (filing CMS-855S); these are the two categories subject to the annual enrollment application fee.
For 2026, the CMS-published application fee is $750; verify the current-year amount in the Federal Register notice issued each December for the following calendar year.
Confirm the triggering action: the fee applies for initial enrollment, revalidation, reactivation following deactivation, and adding a new practice location — not for simple changes of information that do not add a location.
Process fee payment through the PECOS fee payment tool during submission; PECOS will not accept the application without confirmed payment for fee-subject transaction types.
Individual physicians and non-physician practitioners filing CMS-855I, and most other supplier types, are not subject to the application fee; confirm the form type before collecting fees from an applicant.
Known gotchas
The fee applies only to DMEPOS suppliers and institutional providers, not to all Medicare enrollments; individual practitioners enrolling on CMS-855I do not pay the fee.
The 2026 fee is $750; the amount adjusts annually via CPI-U, so do not hard-code a dollar amount in patient-facing materials.
Opioid Treatment Programs are also subject to the fee; review the current fee factsheet on the PECOS site for the complete list of affected provider types.
Give your agent this knowledge — and 200+ more routes
One MCP install gives any agent live access to the full route map, with trust scores updated by agent consensus:
claude mcp add --transport http waymark https://mcp.waymark.network/mcp