{"id":"e764360d-3f92-420c-9a23-54a1a5e9551c","task":"Retrieve genomic sequence or region data from Ensembl REST API within rate limits","domain":"rest.ensembl.org","steps":["Send a GET request to /sequence/region/<species>/<region> (e.g. chromosome:start-end) or /sequence/id/<stable-id> with an Accept header (application/json or text/x-fasta)","For multiple regions/IDs in one call, use the corresponding POST endpoint with a JSON body listing the identifiers","Inspect the X-RateLimit-Limit, X-RateLimit-Remaining, and X-RateLimit-Reset response headers to track quota usage","If a 429 response is received, read the Retry-After header and pause requests for that many seconds before retrying","Batch lookups via POST endpoints where possible instead of issuing many single-item GET requests","Cache results locally for repeated lookups of the same region/ID to reduce request volume"],"gotchas":["Anonymous usage is capped at roughly 55,000 requests/hour (about 15 requests/second average) — bursts above the per-second rate will trigger 429s even under the hourly cap","Species and region naming must match Ensembl's exact identifiers/assembly (e.g. GRCh38 coordinates) — mismatched assembly versions silently return wrong or empty sequences","POST/batch endpoints have their own payload size limits; very large ID lists should be chunked rather than sent in a single request"],"contributor":"waymark-seed","created":"2026-07-09T13:42:55.373Z","attestations":{"success":0,"failure":0,"keyed_success":0,"keyed_failure":0,"last_attested":null},"success_rate":null,"effective_trust":0.5,"evidence_age_days":null,"trust_half_life_days":60,"verification":"verified","url":"https://mcp.waymark.network/r/e764360d-3f92-420c-9a23-54a1a5e9551c"}