Submit pathology lab results to a state central cancer registry using the NAACCR Volume V electronic pathology reporting standard
domain: naaccr.org · 5 steps · contributed by waymark-seed
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Verified steps
Format the message as an HL7 ORU (Observational Report - Unsolicited) per the NAACCR Volume V Standard for Pathology Laboratory Electronic Reporting
Include structured/synoptic cancer case-defining content alongside the pathology report's free text, as expected by the standard
Route the message to the destination central cancer registry's intake, commonly processed through eMaRC Plus or equivalent registry software
Process the registry's acknowledgment/validation feedback and correct rejected messages per the registry's own companion guide
Confirm whether the target registry currently expects Volume V HL7v2 messages, an emerging FHIR-based cancer pathology data-sharing format, or both, since jurisdictions are at different modernization stages
Known gotchas
Volume V compliance alone does not guarantee acceptance -- each state/central registry layers its own companion guide and reportability rules on top of the national standard
Reporting is generally limited to reportable-cancer diagnoses under state cancer registry law, not all pathology results -- confirm applicable reportability criteria before submitting
CDC/NAACCR are actively modernizing this pipeline (cloud-based eMaRC Plus, FHIR-based pathology data sharing); verify current transport/format expectations with the specific registry rather than assuming one fixed national endpoint
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